Hetero atom to carbon ratio

The hetero to carbon ratio is as well a good measure for the likelihood of a sum formula to represent a really existing molecule as this ratio is typically between 0.25 and 1 in biologically relevant molecules. All hetero atoms (all atoms not being carbon and hydrogen) are added together here. We find the hetero to carbon ratio to be normally distributed and the density function of this distribution is used for scoring. The parameter determined in this case (mean = 0.59 and standard deviation = 0.56) are used as default.

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