Molecular Systems Biology is dealing with different types of networks describing metabolism, gene regulation, signal transduction, intercellular communication and so on. The workshop has a focus on methods dealing with the structure of the corresponding biochemical networks, i.e. their topology and/or stoichiometry. This embraces different approaches from the computational and systems sciences:
- Network Reconstruction of biochemical networks from “omics” data sets based on statistical and/or learning methods
- Network Topology, i.e. (local and genome wide) topological analysis of network structure using graph algorithms and visualization of network properties
- Network Analysis for elucidation of network properties by stoichiometric analysis or mapping of experimental data to network structures
Workshop Format:
The workshop consists of two Sessions with 3 – 4 talks (20+10 minutes each).
Registration
An option to enroll for this workshop is offered with the main registration to the GCB 2012. If you want to attend this workshop only, but not the GCB 2012, please mail to margit.leitner@uni-jena.de indicating:
- Your name and degree,
- Your affiliation (including address and phone number), and
- Your profession or subject of study.
This workshop is free of charge for all participants, irrespective of GCB 2012 attendance, but registration is required.
Preliminary Program:
| Network Reconstruction | |
| 11:00 | Jan Baumbach, Saarbrücken Finding expressed key pathways – Combining biological networks with gene expression and epigenetics data |
| 11:30 | Ulrich Mansmann, Munich Title tba |
| Network Topology | |
| 12:00 | Joachim Selbig, Golm Analysis and comparison of cancer-related metabolic networks |
| 12:30 | Katharina Nöh, Jülich Isotope Labeling Networks |
| 13:00 – 14:00 | Lunch Break |
| Network Analysis | |
| 14:00 | Christoph Kaleta, Jena Metabolism and beyond: Identification of new targets of the global regulator PdhR in Escherichia coli |
| 14:30 | Christian von Mering, Zurich Projecting experimental data onto protein interaction network: A case study from RNAi perturbation screens |
| 15:00 | Thomas Dandekar, Würzburg Boolean modeling and semiquantitative models of cellular interactions |
| 15:30 | Final Discussion |
